This issue appears every day here in the Community.
Rule 1 of using Macs is "Don't install junk."
Keep your software updated and macOS is capable of keeping itself secure. MacOS can take care of itself without the need for useless cleaners, optimizers and anti-virus apps.
Clean My Mac is considered by many veteran users to be nothing more than snake oil and likely to cause more problems than it prevents. I've been using well performing Macs for decades without these types of apps. I'd uninstall CMM.
Meanwhile, What you can do...
• Empty the Trash in the Dock.
• Empty the trash in the Photos app.
• Delete unused and unneeded installers from your Downloads folder and desktop.
• Reboot your Mac at least weekly.
• Transfer files that you don’t use daily to an external drive and then delete them from the startup drive and empty the trash. Files that take up the most room are movies, images and music.
• Force Time Machine to delete local snapshots:
About Time Machine local snapshots - Apple Support
• Use Disk Utility to delete APFS snapshots: View APFS snapshots in Disk Utility on Mac - Apple Support
This from Apple on the subject of storage management:
Free up storage space on Mac - Apple Support