Mac won't let me click on parts of my screen

Hi!

My Macbook Pro 16" 2019 is having a very weird issue. I cannot click a certain are of the screen, around the higher portion of my screen in the center a bit to the right. My mouse pointer can go on this specific portion without a problem, but it cannot do a left click or right click. I've tried with my mouse, with my trackpad, I've tried doing it on the desktop or in different apps, I've tried restarting my computer, I've tried updating the software but there is still nothing that works yet.

[Re-Titled by Moderator]