Issue with Logic Pro using my interface for input and output

Logic Pro won't connect to my interface. This problem just started and not sure why. First I noticed when I connected the interface, every plugin on the project I was working in had an error. I tried disengaging the 3rd party plug ins but no change. I opened a new project with no 3rd party plug ins and Logic won't recognize the interface at all. I uninstalled and reinstalled the interface drivers. Tried reinstalling the plug in library. Restarted, updated Logic to 11.2. No changes.