Optimal RAM arrangement for Mac Pro 2013 (12-core, D500)

I have a Mac Pro 2013 (12-core, D500).

I have four RAM modules, each 16 GB:

  • 2 × PC3-14900R-13-13-E2
  • 2 × PC3-14900R-13-12-E2

What is the best way to arrange or install the RAM modules to get the best performance and stability?

this

Slot 1 → PC3-14900R-13-12-E2

Slot 2 → PC3-14900R-13-13-E2

Slot 3 → PC3-14900R-13-12-E2

Slot 4 → PC3-14900R-13-13-E2

or

Slot 1 → PC3-14900R-13-12-E2

Slot 2 → PC3-14900R-13-12-E2

Slot 3 → PC3-14900R-13-13-E2

Slot 4 → PC3-14900R-13-13-E2

Plz help



[Re-Titled by Moderator]

Original Title: MacPro 2013 Memory

Mac Pro, macOS 12.7

Posted on Nov 5, 2025 11:03 PM

Reply
2 replies

Nov 6, 2025 6:55 AM in response to YallaB

Best theoretical setup is matched pairs in adjacent slots. Conventional wisdom is the largest modules go in the lowest numbered slots, so I would be inclined to place the fastest (smaller number of states) in the lowest slots as well.


I don't know whether it will interleave beyond pairs, but whether it does or not, the difference will not be noticeable.

Nov 13, 2025 9:41 PM in response to YallaB

Hi,

It is said that for optimal performance in the 2013 Mac Pro (Cylinder), install matched pairs of ECC registered DIMMs(RDIMMs) in adjacent slots (A1/B1, A2/B2) for quad-channel operation, using the lowest numbered slots (A1, B1) for the first pair and A2/B2 for the second, ensuring all modules are the same speed and type (no heat sinks). This maximizes bandwidth, though differences between configurations might be slight unless heavily taxing the system. 


Optimal RAM arrangement for Mac Pro 2013 (12-core, D500)

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