Normally you don't have to transcode imported videos before editing. In this case, if that seems to work, do that. OBS is often the cause of various downstream problems in video editing. Here is a general explanation:
I would designate as "Tier 1" formats such as ProRes 422 encoded by a licensed product, Sony 10-bit 4:2:2 XAVC-I in the MXF container, etc.
Lacking that, a quality codec from a consumer camera, such as Sony XAVC-S 8-bit 4:2:0 or 10-bit 4:2:2 is generally OK. There are sometimes issues with timecode with that format, and it is less smooth to edit than All-Intra, but most computers and NLEs now support hardware-accelerated decoding, which helps. XAVC from mirrorless cameras uses the MP4 container, for which metadata is not as rich or standardized as MXF, but it still generally works. Formats such as Sony's XAVC family are a restricted subset of the possible H.264/HEVC encoding combinations, so this helps reliability and support. It is similar with Canon's XF-AVC format, which is also a restricted, documented subset of a lower-level encoding stream using H.264 or HEVC. XF-AVC uses only the MP4 container, but it works very well. We rarely see major problems from the above formats, so I would designate those as "Tier 2."
Below Tier 2 are highly compressed formats from devices such as GoPro cameras. Those often are not covered by a vendor-specific application standard such as XAVC, and in general we see more problems from those, but it is usually not disastrous. I would designate those as "Tier 3."
Below Tier 3 are what I call "junk codecs" from things like OBS screen capture, consumer security cameras, automotive dash cameras, oddball frame sizes and resolutions, variable frame rates, and formats resulting from unknown multi-stage transcoding involving unlicensed, untested software. Those I would designate as "Tier 4," and they very frequently cause problems.
Often those problems will manifest as an issue with one particular NLE but not others. To naive consumers, "video is video" and they often report problems from Tier 4 formats as an NLE problem, when in fact it's a problem caused by a "junk codec." It's not really the fault of those users, as the information and tools in this area are scarce. This could be likened to problems caused by "bad gasoline," which may seemingly only affect one type of car. But the solution is not to fix that car, but to realize that standards for gasoline purity must be maintained.
Contributing to these problems is the lack of available technical QA tools. Big places like NetFlix have those, and they can easily fund engineers to design tailor-made QA/QC tools to meet emerging needs. Places like NetFlix have rigid acceptance criteria -- only certain codecs from certain cameras. That's an up-front filter that prevents the junk from getting into their system, and what contaminated video slips through is detected by their sophisticated QA tools.
Smaller content producers cannot be so picky -- they often have to accept video content from many sources. There are also no reliable utilities that perform a thorough inspection for encoding defects, especially for problems commonly encountered with "Tier 4" or "junk" codecs.
Further exacerbating this is the lack of enforcement and regulation of the situation. There is no "codec police" who will give a ticket to producers of problem-ridden junk formats.