Did you try Ivan54's suggestion of Safe Boot yet?
Safe Boot, (holding Shift key down at startup), does the problem occur in Safe Mode? Could take 10 minutes or more.
Safe mode attempts to repair Disks & clears lots of caches & loads safe Drivers, & prevents loading of 3rd party extensions, so if Safe Mode works try again in regular boot.
Delete these files & restart...
~/Library/LaunchAgents/com.adobe.ARM.***.plist
~/Library/LaunchAgents/com.adobe.ARM.***.plist
~/Library/LaunchAgents/org.virtualbox.vboxwebsrv.plist
/Library/LaunchAgents/com.microsoft.update.agent.plist
/Library/LaunchAgents/com.adobe.ccxprocess.plist
~ tilde indicates your home folder
Apple hid the Users' Library folders...
Method 1:
1 From the Finder, select the Go menu at top of the screen, and choose Go to Folder.
2 In the window that opens, enter ~/Library, and click Go.