Preview crash (macOS Big Sur 11.3.1)

Good trouble shooting. Suggest restarting the computer in Safe Mode and log into the problematic Account where the Preview is crashing. It will do a Repair Disk, clear cache files and only load Apple Software, extensions and Fonts. So it will load slowly - normal. Once logged in - run it this mode foe 15 - 20 minutes and Test Preview - does it crash or work normally ?

We use Safe mode to isolate Third Party software / extensions and fonts from loading and to see if the issue is system wide or user Account. The latter, you have already identified as possible User Account.

In addition to what P. Philips said: also run Etrecheck and post its full reply here.

The fact that it works in another account suggests it is an issue in yours, and that is most likely due to some launch agent or login item. The report should points in the right direction.

Agree with @Luis S on the idea of Etrececk. Trusted Developer and Respected Contributor to these Forums. Free to use or paid from Added Features. Run it with Full Disk Access ( Security & Privacy - Full Disk Access The Generated Report will Not Reveal any Personal Information and can be Copy and Paste as reply using the Additional Text Icon 3rd to last Icon below.